This condition has a significant impact on patients’ quality of life and imposes a considerable economic burden. It is estimated that up to 20% of children and 10% of adults worldwide are affected by AD. pseudintermedius may play a role in the development of AD when colonized on the skin, emphasizing the importance of taking preventive measures when in contact with animals.Ītopic dermatitis (AD) is a chronic, recurring inflammatory disease that causes itching. Our findings suggest that animal-origin S. pseudintermedius can effectively induce the Th2 response in vivo. pseudintermedius strain isolated from the lesion site of the AD patient exhibited a higher expression of IL-4 and IL-5 when colonized on mouse skin, as compared to S. aureus in mice, the expression of cytokines interleukin-4 (IL-4) and interleukin-5 (IL-5) were significantly higher in the S. pseudintermedius infection was significantly smaller than that caused by S. Although the skin abscess area resulting from S. aureus demonstrated coordinated antibiotic susceptibility, with ST2384 and ST22 being the respective types. The Multi-locus sequence typing (MLST) of S. aureus, both of which were eradicated after treatment. Our findings indicated that the predominant bacteria colonizing the lesion site of AD were S. We utilized culture and next-generation genomic sequencing (NGS) to identify the bacteria present on the skin swabs taken from the lip sites both prior to and following treatment. In our investigation, we presented a case of cheilitis in a patient with atopic dermatitis (AD). pseudintermedius isolated from the lesion site. As another coagulase-positive Staphylococci, it is crucial to pay more attention to S. Even though Staphylococcus pseudintermedius is an animal-origin pathogen, it is increasingly becoming a source of concern in human diseases. The pathogenic coagulase-positive Staphylococcus aureus is the primary species responsible for the progression of AD. The local skin microbial dysbiosis is a contributing factor to the development of AD. Atopic dermatitis (AD) is an inflammatory skin condition distinguished by an activated Th2 immune response.
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